Friday, September 18, 2026 • 12:15 AM • Highmark Stadium • Prime Video
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Game Highlights
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Closing Odds
SpreadBUF -4.5
TotalO/U 53.5
draftkings:BUF 1/2 (67%)·DET 7/4 (37%)
BUF
DET
38.5
Points/Game
31.0
31.0
Allowed/Game
35.5
38.5
Last 3 PPG
31.0
31.0
Last 3 Allowed
35.5
W2
Streak
L1
25%
Strength of Sched.
50%
Related Coverage
Allen stars as Bills open new stadium in styleThe Buffalo Bills open their new stadium in style with a 41-31 win over the Detroit Lions, as Josh Allen shines again.26m agovia Yahoo Sports
Bills celebrate new Highmark Stadium in style with big winThe Bills threw a heck of a housewarming party for their new Highmark Stadium on Thursday, launching fireworks to open the night and then piling up points in a 41-31 victory over the Detroit Lions that felt more dominant than the final score indicated.3h agovia ESPN
Lions' loss to Bills has panic level high after another poor performance by defenseDetroit has yielded 30 and 41 points in back-to-back games4h agovia CBS Sports